Home | Reagent Consumables | Instrument | Service&Support  | Ordering Information | Contact Us |
GenomeLab™ SNPstream® Genotyping Series
GenomeLab™ SNPstream® Genotyping System--SNP genotyping for medium to ultra-high throughput analysis

GenomeLab SNPstream Genotyping System--
SNP genotyping for medium to ultra-high
throughput analysis

SNP genotyping for medium to ultra-high throughput analysis

The GenomeLab SNPstream Genotyping System provides an automated scalable system capable of performing from 4,600 to over 3,000,000 SNP genotypes per day. Combined with multiplexing capabilities, experimental layouts and operational flexibility, this enables you to process a wide range of studies.

 

Product Features
Click to enlarge image
GenomeLab SNPstream is an automated multiplexed system that can process either 12 or 48 SNPs in each well of an arrayed 384-well plate.

12-plex or 48-plex SNP Genotyping

Click to enlarge image
Hardware
  • In a bench-top design, the GenomeLab SNPstream Genotyping System utilizes single-base primer extension technology in a tagged fluorescent assay to deliver an automated, scalable solution for your medium to ultra-high throughput analysis. It comes with reagents, software and instrumentation developed to work optimally together, as well as a two-color CCD-based imager.


Integrated Software--Fully Automated Workflow From Raw Data to Genotype Summary Report
  • The SNPstream software suite is a comprehensive set of advanced, easy-to-use tools that work together to provide a seamless workflow, from primer design to 384-well setup, analysis of image data, and genotype calls. Large amounts of data in batch format are handled with minimal user interaction for increased data integrity and ultra-high throughput processing.
  • Seamless Workflow--Up to 72 Plates Unattended

SNPware® Reagent Kits

SNPware® Reagent Kits
SNPware Reagent Kits (12- or 48-plex)
  • Our preformulated, ready-to-use SNPware® Reagent Kits are optimized for effortless and robust single-base primer extension reactions. The kits include ready-to-use reagents for simple addition reactions, all performed in the original PCR* plate. No precipitation or filtration steps are required.

SNPware Tag Array Plate

SNPware Tag Array Plate
Tag Array Method
  • Multiplexed reactions are spatially resolved on a SNPware Tag Array plate. Each of the 384 wells in a plate contain 16 or 52 unique oligonucleotides of a known sequence, or tag. Each tag on the plate is complementary to one of the tags of the 12 or 48 extension primers, plus four controls to ensure accuracy. After transfer to the Tag Array plate, each SNP hybridizes to its complementary tag. SNPs are then identified by their position in the well.

More Info


Automation

Our assay setup is compatible with either manual operation or different automated solutons.

Manual pipetting method Manual — The GenomeLab SNPstream's assay setup is easily achieved by manual pipetting.
Automated pipetting with the Biomek® 3000 Laboratory Automation Workstation

Biomek® 3000 — Ideally suited to meet the needs of low- to medium-throughput research applications.

Automated pipetting and medium throughput with the Biomek® NXP Laboratory Automation Workstation Biomek NXP — Available in multiple configurations and provides a high degree of flexibility with medium throughput.
Automated pipetting, high throughput, and complete integration with the Biomek® FXP Laboratory Automation Workstation Biomek FXP — Offers the highest capacity deck space available and the most flexibility in device integration. Provides total application solutions with either single- or dual-bridge configurations that accommodate a variety of pipetting options.

back to top


Autoprimer.com

Click to enlarge image

Autoprimer.com		 This innovative, on-line resource takes the uncertainty out of assay design by providing fast, easy-to-use primer design support and tag assignments. Just upload or enter your sequence at www.autoprimer.com and our state-of-the algorithms will instantly design robust, best-fit multiplex PCR and extension primers. By designing panels to work under a single PCR condition as well as extension conditions, Autoprimer.com software takes care of the optimization--so you don't have to.

back to top


Key Strengths

High Fidelity / Accuracy — Single-base primer extension technology delivers accuracy rates of greater than 99%. This patented method — the gold standard — is the most validated technique available. Our system software allows 100% data QC.
Sensitive — Only 2 ng of DNA is required per sample for either the 12-plex or 48-plex assay. This equates to 0.04 ng DNA required per genotype.
Scalable throughput — Flexible multiplexing and advanced automation provide the capability to process a broad range of 4,600 to over 3,000,000 genotypes per day. Plate-handling robotics increase throughput while providing walk-away operation.
Simple — An integrated bar code reader enables accurate sample tracking and reporting. Our standardized reaction conditions and simple steps mean no optimization is necessary.
Flexibility — All common plate layouts are supplied enabling analyses. Scalable assay automation, automated data collection, data analysis, and auto QC provides a flexible and fully automated solution from DNA to genotype calls.
Cost-effective — By lowering PCR expenses and improving efficiency, the 12-plex 48-plex power built into the GenomeLab SNPstream reduces cost per genotype and per sample.

Multiple DNA Sources — Blood, tissue, cell-culture, swab, etc.

Multiple Species — Human, mouse, cow, drosphilia. microbes, etc.

Service and Assay Support — To help you always get the most out of your Beckman Coulter equipment, we maintain a worldwide reputation for on-line, on-call and on-site support resources. And our experienced applications scientists are available to help you achieve optimum results.

* All trademarks are the property of their respective owners. Where applicable, the PCR process is covered by patents owned by Roche Molecular Systems, Inc., and F. Hoffmann-LaRoche, Ltd.

For Research Use Only; not for use in diagnostic procedures.

Additional Information:

Additional GenomeLab™ Information:

Date：2009/9/25